Footnote 1 11.1 Classes and Descriptions 11.1.1 Class IĬlass I BSCs provide personnel and environmental protection, but offer no product protection ( Figures 11-1a and 11-1b). The physical containment requirements, operational practice requirements, and performance and verification testing requirements relating to BSCs in containment zones regulated by the Public Health Agency of Canada (PHAC) and the Canadian Food Inspection Agency (CFIA) are described in Matrices 3.7, 4.6, and 5.1 of the Canadian Biosafety Standard (CBS), 2 nd Edition. Different manufacturers may have unique design features and new technology in their BSCs. This chapter provides general descriptions of the different types and classes of BSCs. Some classes of BSCs also offer product protection by using HEPA-filtered downflow to flush the cabinet interior of airborne contaminants and to prevent unfiltered inflow air from entering the work area. The air that is exhausted into the surrounding containment zone or directly to the outside atmosphere is passed through high efficiency particulate air (HEPA) filters to protect the environment. Personnel protection is provided through a continuous stream of inward air, known as inflow, which helps prevent aerosols from escaping through the front opening. The various classes and types of BSCs operate under the same basic principles. Chapter 11 - Biological Safety Cabinetsīiological safety cabinets (BSCs) provide effective primary containment for work with infectious material or toxins when they are properly maintained and used in conjunction with good microbiological laboratory practices.
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